Actinic received a request forbidden error from the web server. The server is not properly configured to allow Actinic to run CGI scripts from the cgi-bin.  Run Web | Configure Web Site Details... to review your web site configuration

Suggestions: 
- Check that this folder exists on your server in the place specified in your 'Web | Network Setup' screen and that scripts are allowed to run in it (you may need to contact your host).

 - Check the permissions: 

On Linux/Unix based servers the permissions should be:
cgi-bin (755) – drwxr-xr-x
Online Store Folder (777) – drwxrwxrwx
On Windows based servers (need to be checked with the hosting company): 
IIS
cgi-bin = read/execute
Online Store Folder = read/write/execute
NTFS
cgi-bin = Catalog's FTP account needs 'Change' permissions on the directory
Online Store Folder = Catalog's FTP account needs 'Change' permissions on the directory AND the IUSR_<servername> account needs to have 'Change' permissions on the directory

- There could be a setting in your firewall that could cause this problem.  To test this try turning off your firewall while you perform the upload.  If the upload goes through ok then you will need to find the setting that is causing the problem.