The option to download orders is greyed out.

[KB]

Normally this means that the network settings have changed and the site requires uploading.

If the site is maintained from a separate PC then you should uncheck 'Catalog Maintenance' and 'Design Changes' in 'Settings | Business Settings | Options'.

If both maintenance and order processing is required on the same machine then the site requires an update (Web | Update Website) before orders can be downloaded.