You would need to define a new variable, settable for the products and then change the best sellers layout to use that instead of the full description, you will have to set up the variable for each product. I have just done something similar to this and used block if statements to use the description unless my new variable was defined for the product in which case the new variable was used instead.
There is also a solution in the advanced users guide that shows you how to do this be truncating the description after so many words.
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