I'm not sure just what you're trying to achieve but to make changes to the product layout...
One way is to copy the template called Act_ProductLineLarge.html (or one similar to what you want to end up with) and call it say MyAct_ProductLineLarge.html then edit that file as you need - you can then select to use this layout for the product.
If you want to remove the product description the try removing this line from your Product layout:
NETQUOTEVAR:PRODUCTDESCRIPTION
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